Toxic effects of the soluble skin secretion from the Arabian Gulf catfish (Arius thallasinus, Ruppell) on plasma and liver enzyme levels

J. M. Al-Hassan, M. Ali, M. Thomson, T. Fatima, C. J. Gubler

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21 Scopus citations

Abstract

J. M. Al-Hassan, M. Ali, M. Thomson, T. Fatima and C. J. Gubler. Toxic effects of the soluble skin secretion from the Arabian Gulf catfish (Arius thallasinus, Ruppell) on plasma and liver enzyme levels. Toxicon 23, 532 - 534. 1985. - Injection of skin toxin into the marginal ear vein of rabbits resulted in acute respiratory distress and convulsive movements, followed by death within 7 min. Significant increases in total plasma lactate dehydrogenase and the hepatic and cardiac derived isozymes and in glutamic - oxaloacetic and glutamic - pyruvic transaminase activities were observed in animals receiving toxin. Lower doses of toxin increase the survival time and enzyme levels in plasma. Skin toxin produces a time dependent toxic effect on the liver and heart.

Original languageEnglish
Pages (from-to)532-534
Number of pages3
JournalToxicon
Volume23
Issue number3
DOIs
StatePublished - 1985

Funding Agency

  • Kuwait Foundation for the Advancement of Sciences

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