the genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Georg B. Ehret; Teresa Ferreira; Daniel I. Chasman; Anne U. Jackson; Ellen M. Schmidt; Toby Johnson; Gudmar Thorleifsson; Jian'an Luan; Louise A. Donnelly; Stavroula Kanoni; Ann -Kristin Petersen; Vasyl Pihurl; Rona J. Strawbridge; Dmitry Shungin; Maria F. Hughes; Osorio Meirelles; Marika Kaakinen; Nabila Bouatia-Naji; Kati Kristiansson; Sonia Shah; Marcus E. Kleber; Xiuqing Guo; Leo-Pekka Lyytikainen; Cristiano Fava; Nidas Eriksson; Ilja M. Nolte; Patrik K. Magnusson; Elias L. Salfati; Loukianos S. Rallidis; Elizabeth Theusch; Andrew J. P. Smith; Lasse Folkersen; Kate Witkowska; Tune H. Pers; Roby Joehanes; Stuart K. Kim; Lazaros Lataniotis; Rick Jansen; Andrew D. Johnson; Helen Warren; Young Jin Kim; Wei Zhao; Ying Wu; Bamidele O. Tayo; Murielle Bochud; Devin Absher; Linda S. Adair; Najaf Amin; Dan E. Arkingl; Tomas Axelsson; Damian Baldassarre; Beverley Balkau; Stefania Bandinelli; Michael R. Barnes; Ines Barroso; Stephen Bevan; Joshua C. Bis; Gyda Bjornsdottir; Michael Boehnke; Eric Boerwinkle; Lori L. Bonnycastle; Dorret I. Boomsma; Stefan R. Bornstein; Morris J. Brown; Michel Burnier; Claudia P. Cabrera; John C. Chambers; I-Shou Chang; Ching-Yu Cheng; Peter S. Chines; Ren-Hua Chung; Francis S. Collins; John M. Connell; Angela Doring; Jean Dallongeville; John Danesh; Ulf de Faire; Graciela Delgado; Anna F. Dominiczak; Alex S. F. Doney; Fotios Drenos; Sarah Edkins; John D. Eicher; Roberto Elosua; Stefan Enroth; Jeanette Erdmann; Per Eriksson; Tonu Esko; Evangelos Evangelou; Alun Evans; Tove Fai; Martin Farra; Janine F. Felixl; Jean Ferrieres; Luigi Ferrucci; Myriam Fornage; Terrence Forrester; Nora Franceschinil; Oscar H. Franco; Anders Franco-Cereceda; Ross M. Fraser; Santhi K. Ganesh; He Gao; Karl Gertow; Francesco Gianfagna; Bruna Gigante; Franco Giulianini; Anuj Goe; Alison H. Goodall; Mark Goodarzi; Mathias Gorski; Jurgen Grassler; Christopher J. Groves; Vilmundur Gudnason; Ulf Gyllensten; Goran Hallmans; Anna-Liisa Hartikainen; Maija Hassinen; Aki S. Havulinna; Caroline Hayward; Serge Hercberg; Karl-Heinz Herzig; Andrew A. Hicks; Aroon D. Hingorani; Joel N. Hirschhorn; Albert Hofmanl; Jostein Holmen; Oddgeir Lingaas Holmen; Jouke-Jan Hottenga; Phil Howard; Chao A. Hsiung; Steven C. Hunt; M. Arfan Ikram; Thomas Illig; Carlos Iribarren; Richard A. Jensen; Mika Kahonen; Hyun Min Kang; Sekar Kathiresan; Brendan J. Keating; Kay-Tee Khaw; Yun Kyoung Kim; Eric Kim; Mika Kivimaki; Norman Klopp; Genovefa Kolovou; Pirjo Komulainen; Jaspal S. Kooner; Gulum Kosova; Ronald M. Krauss; Diana Kuh; Zoltan Kutalik; Johanna Kuusisto; Kirsti Kvaloy; Timo A. Lakka; Nanette R. Lee; I-Te Lee; Wen-Jane Lee; Daniel Levy; Xiaohui Li; Kae-Woei Liang; Honghuang Lin; Li Lin; Jaana Lindstrom; Stephane Lobbens; Satu Mannisto; Gabriele Muller; Martina Muller-Nurasyid; Francois Mach; Hugh S. Markus; Eirini Marouli; Mark I. McCarthy; Colin A. McKenzie; Pierre Meneton; Cristina Menni; Andres Metspalu; Vladan Mijatovic; Leena Moilanen; May E. Montasser; Andrew D. Morris; Alanna C. Morrison; Antonella Mulas; Ramaiah Nagaraja; Narisu Narisu; Kjell Nikus; Christopher J. O'Donnell; Paul F. O'Reilly; Ken K. Ong; Fred Paccaud; Cameron D. Palmer; Afshin Parsa; Nancy L. Pedersen; Brenda W. Penninx; Markus Perola; Annette Peters; Neil Poulter; Peter P. Pramstaller; Bruce M. Psaty; Thomas Quertermous; Dabeeru C. Rao; et al.

doi:10.1038/ng.3667

the genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Georg B. Ehret, Teresa Ferreira, Daniel I. Chasman, Anne U. Jackson, Ellen M. Schmidt, Toby Johnson, Gudmar Thorleifsson, Jian'an Luan, Louise A. Donnelly, Stavroula Kanoni, Ann -Kristin Petersen, Vasyl Pihurl, Rona J. Strawbridge, Dmitry Shungin, Maria F. Hughes, Osorio Meirelles, Marika Kaakinen, Nabila Bouatia-Naji, Kati Kristiansson, Sonia ShahMarcus E. Kleber, Xiuqing Guo, Leo-Pekka Lyytikainen, Cristiano Fava, Nidas Eriksson, Ilja M. Nolte, Patrik K. Magnusson, Elias L. Salfati, Loukianos S. Rallidis, Elizabeth Theusch, Andrew J. P. Smith, Lasse Folkersen, Kate Witkowska, Tune H. Pers, Roby Joehanes, Stuart K. Kim, Lazaros Lataniotis, Rick Jansen, Andrew D. Johnson, Helen Warren, Young Jin Kim, Wei Zhao, Ying Wu, Bamidele O. Tayo, Murielle Bochud, Devin Absher, Linda S. Adair, Najaf Amin, Dan E. Arkingl, Tomas Axelsson, Damian Baldassarre, Beverley Balkau, Stefania Bandinelli, Michael R. Barnes, Ines Barroso, Stephen Bevan, Joshua C. Bis, Gyda Bjornsdottir, Michael Boehnke, Eric Boerwinkle, Lori L. Bonnycastle, Dorret I. Boomsma, Stefan R. Bornstein, Morris J. Brown, Michel Burnier, Claudia P. Cabrera, John C. Chambers, I-Shou Chang, Ching-Yu Cheng, Peter S. Chines, Ren-Hua Chung, Francis S. Collins, John M. Connell, Angela Doring, Jean Dallongeville, John Danesh, Ulf de Faire, Graciela Delgado, Anna F. Dominiczak, Alex S. F. Doney, Fotios Drenos, Sarah Edkins, John D. Eicher, Roberto Elosua, Stefan Enroth, Jeanette Erdmann, Per Eriksson, Tonu Esko, Evangelos Evangelou, Alun Evans, Tove Fai, Martin Farra, Janine F. Felixl, Jean Ferrieres, Luigi Ferrucci, Myriam Fornage, Terrence Forrester, Nora Franceschinil, Oscar H. Franco, Anders Franco-Cereceda, Ross M. Fraser, Santhi K. Ganesh, He Gao, Karl Gertow, Francesco Gianfagna, Bruna Gigante, Franco Giulianini, Anuj Goe, Alison H. Goodall, Mark Goodarzi, Mathias Gorski, Jurgen Grassler, Christopher J. Groves, Vilmundur Gudnason, Ulf Gyllensten, Goran Hallmans, Anna-Liisa Hartikainen, Maija Hassinen, Aki S. Havulinna, Caroline Hayward, Serge Hercberg, Karl-Heinz Herzig, Andrew A. Hicks, Aroon D. Hingorani, Joel N. Hirschhorn, Albert Hofmanl, Jostein Holmen, Oddgeir Lingaas Holmen, Jouke-Jan Hottenga, Phil Howard, Chao A. Hsiung, Steven C. Hunt, M. Arfan Ikram, Thomas Illig, Carlos Iribarren, Richard A. Jensen, Mika Kahonen, Hyun Min Kang, Sekar Kathiresan, Brendan J. Keating, Kay-Tee Khaw, Yun Kyoung Kim, Eric Kim, Mika Kivimaki, Norman Klopp, Genovefa Kolovou, Pirjo Komulainen, Jaspal S. Kooner, Gulum Kosova, Ronald M. Krauss, Diana Kuh, Zoltan Kutalik, Johanna Kuusisto, Kirsti Kvaloy, Timo A. Lakka, Nanette R. Lee, I-Te Lee, Wen-Jane Lee, Daniel Levy, Xiaohui Li, Kae-Woei Liang, Honghuang Lin, Li Lin, Jaana Lindstrom, Stephane Lobbens, Satu Mannisto, Gabriele Muller, Martina Muller-Nurasyid, Francois Mach, Hugh S. Markus, Eirini Marouli, Mark I. McCarthy, Colin A. McKenzie, Pierre Meneton, Cristina Menni, Andres Metspalu, Vladan Mijatovic, Leena Moilanen, May E. Montasser, Andrew D. Morris, Alanna C. Morrison, Antonella Mulas, Ramaiah Nagaraja, Narisu Narisu, Kjell Nikus, Christopher J. O'Donnell, Paul F. O'Reilly, Ken K. Ong, Fred Paccaud, Cameron D. Palmer, Afshin Parsa, Nancy L. Pedersen, Brenda W. Penninx, Markus Perola, Annette Peters, Neil Poulter, Peter P. Pramstaller, Bruce M. Psaty, Thomas Quertermous, Dabeeru C. Rao, et al.

Research output: Contribution to journal › Article › peer-review

328 Scopus citations

Original language	American English
Pages (from-to)	1171-1184
Number of pages	14
Journal	Nature Genetics
Volume	48
Issue number	10
DOIs	https://doi.org/10.1038/ng.3667
State	Published - 2016
Externally published	Yes

Funding Agency

Kuwait Foundation for the Advancement of Sciences

Access to Document

10.1038/ng.3667

Cite this

Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A. .-K., Pihurl, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K., ... al., E. (2016). the genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics, 48(10), 1171-1184. https://doi.org/10.1038/ng.3667

@article{004869f2b0fd401eba29ab90950179a6,

title = "the genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals",

author = "Ehret, {Georg B.} and Teresa Ferreira and Chasman, {Daniel I.} and Jackson, {Anne U.} and Schmidt, {Ellen M.} and Toby Johnson and Gudmar Thorleifsson and Jian'an Luan and Donnelly, {Louise A.} and Stavroula Kanoni and Petersen, {Ann -Kristin} and Vasyl Pihurl and Strawbridge, {Rona J.} and Dmitry Shungin and Hughes, {Maria F.} and Osorio Meirelles and Marika Kaakinen and Nabila Bouatia-Naji and Kati Kristiansson and Sonia Shah and Kleber, {Marcus E.} and Xiuqing Guo and Leo-Pekka Lyytikainen and Cristiano Fava and Nidas Eriksson and Nolte, {Ilja M.} and Magnusson, {Patrik K.} and Salfati, {Elias L.} and Rallidis, {Loukianos S.} and Elizabeth Theusch and Smith, {Andrew J. P.} and Lasse Folkersen and Kate Witkowska and Pers, {Tune H.} and Roby Joehanes and Kim, {Stuart K.} and Lazaros Lataniotis and Rick Jansen and Johnson, {Andrew D.} and Helen Warren and Kim, {Young Jin} and Wei Zhao and Ying Wu and Tayo, {Bamidele O.} and Murielle Bochud and Devin Absher and Adair, {Linda S.} and Najaf Amin and Arkingl, {Dan E.} and Tomas Axelsson and Damian Baldassarre and Beverley Balkau and Stefania Bandinelli and Barnes, {Michael R.} and Ines Barroso and Stephen Bevan and Bis, {Joshua C.} and Gyda Bjornsdottir and Michael Boehnke and Eric Boerwinkle and Bonnycastle, {Lori L.} and Boomsma, {Dorret I.} and Bornstein, {Stefan R.} and Brown, {Morris J.} and Michel Burnier and Cabrera, {Claudia P.} and Chambers, {John C.} and I-Shou Chang and Ching-Yu Cheng and Chines, {Peter S.} and Ren-Hua Chung and Collins, {Francis S.} and Connell, {John M.} and Angela Doring and Jean Dallongeville and John Danesh and {de Faire}, Ulf and Graciela Delgado and Dominiczak, {Anna F.} and Doney, {Alex S. F.} and Fotios Drenos and Sarah Edkins and Eicher, {John D.} and Roberto Elosua and Stefan Enroth and Jeanette Erdmann and Per Eriksson and Tonu Esko and Evangelos Evangelou and Alun Evans and Tove Fai and Martin Farra and Felixl, {Janine F.} and Jean Ferrieres and Luigi Ferrucci and Myriam Fornage and Terrence Forrester and Nora Franceschinil and Franco, {Oscar H.} and Anders Franco-Cereceda and Fraser, {Ross M.} and Ganesh, {Santhi K.} and He Gao and Karl Gertow and Francesco Gianfagna and Bruna Gigante and Franco Giulianini and Anuj Goe and Goodall, {Alison H.} and Mark Goodarzi and Mathias Gorski and Jurgen Grassler and Groves, {Christopher J.} and Vilmundur Gudnason and Ulf Gyllensten and Goran Hallmans and Anna-Liisa Hartikainen and Maija Hassinen and Havulinna, {Aki S.} and Caroline Hayward and Serge Hercberg and Karl-Heinz Herzig and Hicks, {Andrew A.} and Hingorani, {Aroon D.} and Hirschhorn, {Joel N.} and Albert Hofmanl and Jostein Holmen and Holmen, {Oddgeir Lingaas} and Jouke-Jan Hottenga and Phil Howard and Hsiung, {Chao A.} and Hunt, {Steven C.} and Ikram, {M. Arfan} and Thomas Illig and Carlos Iribarren and Jensen, {Richard A.} and Mika Kahonen and Kang, {Hyun Min} and Sekar Kathiresan and Keating, {Brendan J.} and Kay-Tee Khaw and Kim, {Yun Kyoung} and Eric Kim and Mika Kivimaki and Norman Klopp and Genovefa Kolovou and Pirjo Komulainen and Kooner, {Jaspal S.} and Gulum Kosova and Krauss, {Ronald M.} and Diana Kuh and Zoltan Kutalik and Johanna Kuusisto and Kirsti Kvaloy and Lakka, {Timo A.} and Lee, {Nanette R.} and I-Te Lee and Wen-Jane Lee and Daniel Levy and Xiaohui Li and Kae-Woei Liang and Honghuang Lin and Li Lin and Jaana Lindstrom and Stephane Lobbens and Satu Mannisto and Gabriele Muller and Martina Muller-Nurasyid and Francois Mach and Markus, {Hugh S.} and Eirini Marouli and McCarthy, {Mark I.} and McKenzie, {Colin A.} and Pierre Meneton and Cristina Menni and Andres Metspalu and Vladan Mijatovic and Leena Moilanen and Montasser, {May E.} and Morris, {Andrew D.} and Morrison, {Alanna C.} and Antonella Mulas and Ramaiah Nagaraja and Narisu Narisu and Kjell Nikus and O'Donnell, {Christopher J.} and O'Reilly, {Paul F.} and Ong, {Ken K.} and Fred Paccaud and Palmer, {Cameron D.} and Afshin Parsa and Pedersen, {Nancy L.} and Penninx, {Brenda W.} and Markus Perola and Annette Peters and Neil Poulter and Pramstaller, {Peter P.} and Psaty, {Bruce M.} and Thomas Quertermous and Rao, {Dabeeru C.} and et al.",

year = "2016",

doi = "10.1038/ng.3667",

language = "American English",

volume = "48",

pages = "1171--1184",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Research",

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TY - JOUR

T1 - the genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

AU - Ehret, Georg B.

AU - Ferreira, Teresa

AU - Chasman, Daniel I.

AU - Jackson, Anne U.

AU - Schmidt, Ellen M.

AU - Johnson, Toby

AU - Thorleifsson, Gudmar

AU - Luan, Jian'an

AU - Donnelly, Louise A.

AU - Kanoni, Stavroula

AU - Petersen, Ann -Kristin

AU - Pihurl, Vasyl

AU - Strawbridge, Rona J.

AU - Shungin, Dmitry

AU - Hughes, Maria F.

AU - Meirelles, Osorio

AU - Kaakinen, Marika

AU - Bouatia-Naji, Nabila

AU - Kristiansson, Kati

AU - Shah, Sonia

AU - Kleber, Marcus E.

AU - Guo, Xiuqing

AU - Lyytikainen, Leo-Pekka

AU - Fava, Cristiano

AU - Eriksson, Nidas

AU - Nolte, Ilja M.

AU - Magnusson, Patrik K.

AU - Salfati, Elias L.

AU - Rallidis, Loukianos S.

AU - Theusch, Elizabeth

AU - Smith, Andrew J. P.

AU - Folkersen, Lasse

AU - Witkowska, Kate

AU - Pers, Tune H.

AU - Joehanes, Roby

AU - Kim, Stuart K.

AU - Lataniotis, Lazaros

AU - Jansen, Rick

AU - Johnson, Andrew D.

AU - Warren, Helen

AU - Kim, Young Jin

AU - Zhao, Wei

AU - Wu, Ying

AU - Tayo, Bamidele O.

AU - Bochud, Murielle

AU - Absher, Devin

AU - Adair, Linda S.

AU - Amin, Najaf

AU - Arkingl, Dan E.

AU - Axelsson, Tomas

AU - Baldassarre, Damian

AU - Balkau, Beverley

AU - Bandinelli, Stefania

AU - Barnes, Michael R.

AU - Barroso, Ines

AU - Bevan, Stephen

AU - Bis, Joshua C.

AU - Bjornsdottir, Gyda

AU - Boehnke, Michael

AU - Boerwinkle, Eric

AU - Bonnycastle, Lori L.

AU - Boomsma, Dorret I.

AU - Bornstein, Stefan R.

AU - Brown, Morris J.

AU - Burnier, Michel

AU - Cabrera, Claudia P.

AU - Chambers, John C.

AU - Chang, I-Shou

AU - Cheng, Ching-Yu

AU - Chines, Peter S.

AU - Chung, Ren-Hua

AU - Collins, Francis S.

AU - Connell, John M.

AU - Doring, Angela

AU - Dallongeville, Jean

AU - Danesh, John

AU - de Faire, Ulf

AU - Delgado, Graciela

AU - Dominiczak, Anna F.

AU - Doney, Alex S. F.

AU - Drenos, Fotios

AU - Edkins, Sarah

AU - Eicher, John D.

AU - Elosua, Roberto

AU - Enroth, Stefan

AU - Erdmann, Jeanette

AU - Eriksson, Per

AU - Esko, Tonu

AU - Evangelou, Evangelos

AU - Evans, Alun

AU - Fai, Tove

AU - Farra, Martin

AU - Felixl, Janine F.

AU - Ferrieres, Jean

AU - Ferrucci, Luigi

AU - Fornage, Myriam

AU - Forrester, Terrence

AU - Franceschinil, Nora

AU - Franco, Oscar H.

AU - Franco-Cereceda, Anders

AU - Fraser, Ross M.

AU - Ganesh, Santhi K.

AU - Gao, He

AU - Gertow, Karl

AU - Gianfagna, Francesco

AU - Gigante, Bruna

AU - Giulianini, Franco

AU - Goe, Anuj

AU - Goodall, Alison H.

AU - Goodarzi, Mark

AU - Gorski, Mathias

AU - Grassler, Jurgen

AU - Groves, Christopher J.

AU - Gudnason, Vilmundur

AU - Gyllensten, Ulf

AU - Hallmans, Goran

AU - Hartikainen, Anna-Liisa

AU - Hassinen, Maija

AU - Havulinna, Aki S.

AU - Hayward, Caroline

AU - Hercberg, Serge

AU - Herzig, Karl-Heinz

AU - Hicks, Andrew A.

AU - Hingorani, Aroon D.

AU - Hirschhorn, Joel N.

AU - Hofmanl, Albert

AU - Holmen, Jostein

AU - Holmen, Oddgeir Lingaas

AU - Hottenga, Jouke-Jan

AU - Howard, Phil

AU - Hsiung, Chao A.

AU - Hunt, Steven C.

AU - Ikram, M. Arfan

AU - Illig, Thomas

AU - Iribarren, Carlos

AU - Jensen, Richard A.

AU - Kahonen, Mika

AU - Kang, Hyun Min

AU - Kathiresan, Sekar

AU - Keating, Brendan J.

AU - Khaw, Kay-Tee

AU - Kim, Yun Kyoung

AU - Kim, Eric

AU - Kivimaki, Mika

AU - Klopp, Norman

AU - Kolovou, Genovefa

AU - Komulainen, Pirjo

AU - Kooner, Jaspal S.

AU - Kosova, Gulum

AU - Krauss, Ronald M.

AU - Kuh, Diana

AU - Kutalik, Zoltan

AU - Kuusisto, Johanna

AU - Kvaloy, Kirsti

AU - Lakka, Timo A.

AU - Lee, Nanette R.

AU - Lee, I-Te

AU - Lee, Wen-Jane

AU - Levy, Daniel

AU - Li, Xiaohui

AU - Liang, Kae-Woei

AU - Lin, Honghuang

AU - Lin, Li

AU - Lindstrom, Jaana

AU - Lobbens, Stephane

AU - Mannisto, Satu

AU - Muller, Gabriele

AU - Muller-Nurasyid, Martina

AU - Mach, Francois

AU - Markus, Hugh S.

AU - Marouli, Eirini

AU - McCarthy, Mark I.

AU - McKenzie, Colin A.

AU - Meneton, Pierre

AU - Menni, Cristina

AU - Metspalu, Andres

AU - Mijatovic, Vladan

AU - Moilanen, Leena

AU - Montasser, May E.

AU - Morris, Andrew D.

AU - Morrison, Alanna C.

AU - Mulas, Antonella

AU - Nagaraja, Ramaiah

AU - Narisu, Narisu

AU - Nikus, Kjell

AU - O'Donnell, Christopher J.

AU - O'Reilly, Paul F.

AU - Ong, Ken K.

AU - Paccaud, Fred

AU - Palmer, Cameron D.

AU - Parsa, Afshin

AU - Pedersen, Nancy L.

AU - Penninx, Brenda W.

AU - Perola, Markus

AU - Peters, Annette

AU - Poulter, Neil

AU - Pramstaller, Peter P.

AU - Psaty, Bruce M.

AU - Quertermous, Thomas

AU - Rao, Dabeeru C.

AU - al., et

PY - 2016

Y1 - 2016

U2 - 10.1038/ng.3667

DO - 10.1038/ng.3667

M3 - Article

SN - 1061-4036

VL - 48

SP - 1171

EP - 1184

JO - Nature Genetics

JF - Nature Genetics

IS - 10

ER -