Isolation of Cryptococcus magnus and Cryptococcus chernovii from nasal cavities of pediatric patients with acute lymphoblastic leukemia

Ziauddin Khan; Eiman Mokaddas; Suhail Ahmad; Mona H.A. Burhamah

doi:10.3109/13693786.2010.530696

Isolation of Cryptococcus magnus and Cryptococcus chernovii from nasal cavities of pediatric patients with acute lymphoblastic leukemia

Ziauddin Khan, Eiman Mokaddas, Suhail Ahmad, Mona H.A. Burhamah

Kuwait University

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

We report the isolation of Cryptococcus magnus and Cryptococcus chernovii in cultures inoculated with nasal specimens of pediatric cancer patients with acute lymphoblastic leukemia. The phenotypic characteristics of the isolates are described and their identity confirmed by sequencing of rDNA. Both species were resistant to caspofungin, anidulafungin, 5-flucytosine and itraconazole, but susceptible to amphotericin B, posaconazole and voriconazole. To the best of our knowledge, the isolation of these two species from nasal cavities has not been reported previously.

Original language	English
Pages (from-to)	439-443
Number of pages	5
Journal	Medical Mycology
Volume	49
Issue number	4
DOIs	https://doi.org/10.3109/13693786.2010.530696
State	Published - May 2011

Keywords

Cryptococcus chernovii
Cryptococcus magnus
cancer patients
isolation
nasal culture

Funding Agency

Kuwait Foundation for the Advancement of Sciences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3109/13693786.2010.530696

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title = "Isolation of Cryptococcus magnus and Cryptococcus chernovii from nasal cavities of pediatric patients with acute lymphoblastic leukemia",

abstract = "We report the isolation of Cryptococcus magnus and Cryptococcus chernovii in cultures inoculated with nasal specimens of pediatric cancer patients with acute lymphoblastic leukemia. The phenotypic characteristics of the isolates are described and their identity confirmed by sequencing of rDNA. Both species were resistant to caspofungin, anidulafungin, 5-flucytosine and itraconazole, but susceptible to amphotericin B, posaconazole and voriconazole. To the best of our knowledge, the isolation of these two species from nasal cavities has not been reported previously.",

keywords = "Cryptococcus chernovii, Cryptococcus magnus, cancer patients, isolation, nasal culture",

author = "Ziauddin Khan and Eiman Mokaddas and Suhail Ahmad and Burhamah, {Mona H.A.}",

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T1 - Isolation of Cryptococcus magnus and Cryptococcus chernovii from nasal cavities of pediatric patients with acute lymphoblastic leukemia

AU - Khan, Ziauddin

AU - Mokaddas, Eiman

AU - Ahmad, Suhail

AU - Burhamah, Mona H.A.

PY - 2011/5

Y1 - 2011/5

N2 - We report the isolation of Cryptococcus magnus and Cryptococcus chernovii in cultures inoculated with nasal specimens of pediatric cancer patients with acute lymphoblastic leukemia. The phenotypic characteristics of the isolates are described and their identity confirmed by sequencing of rDNA. Both species were resistant to caspofungin, anidulafungin, 5-flucytosine and itraconazole, but susceptible to amphotericin B, posaconazole and voriconazole. To the best of our knowledge, the isolation of these two species from nasal cavities has not been reported previously.

AB - We report the isolation of Cryptococcus magnus and Cryptococcus chernovii in cultures inoculated with nasal specimens of pediatric cancer patients with acute lymphoblastic leukemia. The phenotypic characteristics of the isolates are described and their identity confirmed by sequencing of rDNA. Both species were resistant to caspofungin, anidulafungin, 5-flucytosine and itraconazole, but susceptible to amphotericin B, posaconazole and voriconazole. To the best of our knowledge, the isolation of these two species from nasal cavities has not been reported previously.

KW - Cryptococcus chernovii

KW - Cryptococcus magnus

KW - cancer patients

KW - isolation

KW - nasal culture

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DO - 10.3109/13693786.2010.530696

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JO - Medical Mycology

JF - Medical Mycology

IS - 4

ER -

Isolation of Cryptococcus magnus and Cryptococcus chernovii from nasal cavities of pediatric patients with acute lymphoblastic leukemia

Abstract

Keywords

Funding Agency

UN SDGs

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