dietary changes and cognition over 2 years within a multidomain intervention trial-the finnish geriatric intervention study to prevent cognitive impairment and disability (finger)

Jenni Lehtisalo, Esko Levlahti, Jaana Lindstrom, Tuomo Hanninen, Teemu Paajanen, Markku Peltonen, Riitta Antikainen, Tiina Laatikainen, Timo Strandberg, Hilkka Soininen, Jaakko Tuomilehto, Miia Kivipelto, Tiia Ngandu

Research output: Contribution to journalArticlepeer-review

74 Scopus citations

Abstract

AbstractIntroductionAssociation between healthy diet and better cognition is well established, but evidence is limited to evaluate the effect of dietary changes adopted in older age.MethodsWe investigated the role of dietary changes in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) with 1260 at‐risk participants (60–77 years) who were randomized to intensive multidomain intervention (including dietary counseling) or regular health advice for 2 years. Parallel process latent growth curves of adherence to dietary recommendations and cognitive performance were analyzed.ResultsAdherence to healthy diet at baseline predicted improvement in global cognition, regardless of intervention allocation (P = .003). Dietary improvement was associated with beneficial changes in executive function, especially in the intervention group (P = .008; P = .051 for groups combined).DiscussionDietary changes initiated during the intervention were related to changes in executive function in 2 years. Long‐term diet appeared more influential for global cognition.
Original languageAmerican English
Pages (from-to)410-417
Number of pages8
JournalALZHEIMERS & DEMENTIA
Volume15
Issue number3
DOIs
StatePublished - 2019
Externally publishedYes

Funding Agency

  • Kuwait Foundation for the Advancement of Sciences

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