TY - JOUR
T1 - An audit of clinical practice in a single centre in Kuwait
T2 - Management of children on continuous subcutaneous insulin infusion and cardiovascular risk factors screening
AU - Omar, Dina
AU - Alsanae, Hala
AU - Al Khawari, Mona
AU - Abdulrasoul, Majedah
AU - Rahme, Zahraa
AU - Al Refaei, Faisal
AU - Behbehani, Kazem
AU - Shaltout, Azza
N1 - Publisher Copyright:
© 2017 Omar et al.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Objectives: To audit the current clinical practice of continuous subcutaneous insulin infusion (CSII) for the treatment of type 1 diabetes mellitus (T1D) in children and adolescents attending a single centre in Kuwait. Methods: A one year retrospective audit was performed in children and adolescents with T1D on CSII, who attended the paediatric diabetes clinic, Dasman Diabetes Institute during 2012. The primary outcome measure was glycaemic control as evidenced by glycated haemoglobin (HbA1c) level and the secondary outcome measures were the frequency of monitoring of the risk for microvascular complications and occurrence of acute complications and adverse events. Results: 58 children and adolescents (mean age ± SD: 12.6 ± 4.1 years) were included. Mean HbA1c at baseline was 8.8% (72.7 mmol/mol) and 8.9% (73.8 mmol/mol) at the end of a 12 months observation period. Children with poor control (HbA1c >9.5% (80 mmol/mol) had a significant 1.4% reduction in HbA1c compared with the overall reduction of 0.1% (p=0.7). Rate of screening for cardiovascular risk factors and for long term complications were well documented. However, there was underreporting of acute complications such as severe hypoglycaemia and diabetic ketoacidosis. Only 1.7% of patients discontinued the pump. Conclusion: There was no significant change in HbA1c values at the end of 12 months follow up. However, HbA1c values in poorly controlled children improved. CSII requires care by skilled health professionals as well as education and selection of motivated parents and children.
AB - Objectives: To audit the current clinical practice of continuous subcutaneous insulin infusion (CSII) for the treatment of type 1 diabetes mellitus (T1D) in children and adolescents attending a single centre in Kuwait. Methods: A one year retrospective audit was performed in children and adolescents with T1D on CSII, who attended the paediatric diabetes clinic, Dasman Diabetes Institute during 2012. The primary outcome measure was glycaemic control as evidenced by glycated haemoglobin (HbA1c) level and the secondary outcome measures were the frequency of monitoring of the risk for microvascular complications and occurrence of acute complications and adverse events. Results: 58 children and adolescents (mean age ± SD: 12.6 ± 4.1 years) were included. Mean HbA1c at baseline was 8.8% (72.7 mmol/mol) and 8.9% (73.8 mmol/mol) at the end of a 12 months observation period. Children with poor control (HbA1c >9.5% (80 mmol/mol) had a significant 1.4% reduction in HbA1c compared with the overall reduction of 0.1% (p=0.7). Rate of screening for cardiovascular risk factors and for long term complications were well documented. However, there was underreporting of acute complications such as severe hypoglycaemia and diabetic ketoacidosis. Only 1.7% of patients discontinued the pump. Conclusion: There was no significant change in HbA1c values at the end of 12 months follow up. However, HbA1c values in poorly controlled children improved. CSII requires care by skilled health professionals as well as education and selection of motivated parents and children.
KW - Audit
KW - Continuous subcutaneous insulin infusion
KW - Diabetes control and complications trial (DCCT)
KW - Diabetes pump therapy
KW - Glycated haemoglobin (HBA1C)
KW - Hypoglycaemia
KW - Type 1 diabetes mellitus
UR - https://www.scopus.com/pages/publications/85017193835
U2 - 10.2174/1874192401711010019
DO - 10.2174/1874192401711010019
M3 - Article
AN - SCOPUS:85017193835
SN - 1874-1924
VL - 11
SP - 19
EP - 27
JO - Open Cardiovascular Medicine Journal
JF - Open Cardiovascular Medicine Journal
ER -