Project Details
Abstract English
Background:
The outbreak coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) has formed health crisis globally on the whole population and especially in children. The impact of COVID-19 on children has so far been mild, except in children with comorbidities such as type 1 diabetes (T1D) (1, 2). These current times are extremely stressful, and It has been reported that the incidence of T1D was higher during catastrophic events such as the Chernobyl incident in 1986 and the Los Angeles earthquake in 1994 (3, 4). During these pandemics, the possible
consequence on incidence of T1D might be secondary to the psychological stress It poses o the children; in which the infection may be considered a trigger. Also, associated- autoimmune diseases with T1D might be liked to increased incidence of T1D in conjunction with COVID-19 infection.
Objective:
The objective of this study is to determine the incidence of T1D in newly diagnosed children aged ≤ 14 years old during COVID-19 pandemic at MoH & KOC hospitals. A secondary objective is to determine the rate of T1D associated- autoimmune disease in newly diagnosed children and compare it with the previous years prior to pandemic. Also, DKA, its severity, and frequency will be assessed along with acute COVID-19 infection, symptoms, and its complications.
Methodology:
Children who are newly diagnosed with T1D at MoH & KOC hospitals from February 2020 till February 2022 will be recruited or when the pandemic ends (whichever comes first). International Society of Pediatric and Adolescent diabetes (ISPAD) guidelines will be used to confirm the diagnosis of T1D. The
study involves review of medical records, lab results, clinical assessments at presentation and longitudinal follow-up for a duration of 10 years. Also, informed consent will be obtained from both parents and assents for blood investigations. Data will be disclosed from established registries in which the children are
registered.
The outbreak coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) has formed health crisis globally on the whole population and especially in children. The impact of COVID-19 on children has so far been mild, except in children with comorbidities such as type 1 diabetes (T1D) (1, 2). These current times are extremely stressful, and It has been reported that the incidence of T1D was higher during catastrophic events such as the Chernobyl incident in 1986 and the Los Angeles earthquake in 1994 (3, 4). During these pandemics, the possible
consequence on incidence of T1D might be secondary to the psychological stress It poses o the children; in which the infection may be considered a trigger. Also, associated- autoimmune diseases with T1D might be liked to increased incidence of T1D in conjunction with COVID-19 infection.
Objective:
The objective of this study is to determine the incidence of T1D in newly diagnosed children aged ≤ 14 years old during COVID-19 pandemic at MoH & KOC hospitals. A secondary objective is to determine the rate of T1D associated- autoimmune disease in newly diagnosed children and compare it with the previous years prior to pandemic. Also, DKA, its severity, and frequency will be assessed along with acute COVID-19 infection, symptoms, and its complications.
Methodology:
Children who are newly diagnosed with T1D at MoH & KOC hospitals from February 2020 till February 2022 will be recruited or when the pandemic ends (whichever comes first). International Society of Pediatric and Adolescent diabetes (ISPAD) guidelines will be used to confirm the diagnosis of T1D. The
study involves review of medical records, lab results, clinical assessments at presentation and longitudinal follow-up for a duration of 10 years. Also, informed consent will be obtained from both parents and assents for blood investigations. Data will be disclosed from established registries in which the children are
registered.
| Status | Finished |
|---|---|
| Effective start/end date | 1/01/22 → 1/01/25 |
Collaborative partners
- Dasman Diabetes Institute
- Kuwait University
- Ministry of Health
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